Career Employer

Your FREE DANB Infection Control (ICE) Practice Test 2026 – 160+ Q&A

Prepare with realistic, DANB ICE exam-style questions — take the full 75-question test or focused Disease Transmission, Cross-contamination, Instrument Processing, and Occupational Safety drills, each with answer explanations.

Master questions to boost your score

How ready are you?

To find us again, just search “Career Employer DANB ICE

By

Click Start Test above to launch a full-length, 75-question DANB ICE practice test, or drill a single domain — Prevention of Disease Transmission, Prevention of Cross-contamination, Process Instruments and Devices, or Occupational Safety and Administration Protocols. Every question includes a clear explanation so you learn the reasoning, not just the answer.

The Infection Control (ICE) exam is administered by DANB — the Dental Assisting National Board. It is a component of three credentials: the Certified Dental Assistant (CDA), the National Entry Level Dental Assistant (NELDA), and the Certified Orthodontic Assistant (COA).[1]

DANB builds the ICE exam directly on CDC dental infection-control guidance and OSHA standards, so the best preparation is realistic, blueprint-weighted practice grounded in those same sources. That is exactly what this free DANB ICE practice test is built for.[2]

DANB ICE at a Glance

The ICE exam is short, focused, and computer-adaptive. Here are the key facts your practice should mirror:

DANB ICE at a glance
DetailDANB ICE
Certifying BodyDANB (Dental Assisting National Board)
Counts TowardCDA, NELDA, and COA certifications
Questions75 multiple-choice
Time Limit60 minutes
FormatComputer-adaptive testing (CAT)
DeliveryIn-person test center or remote online proctoring
LanguagesEnglish and Spanish
Score Scale100–900
Passing Score400+ scaled score
EligibilityNone — open to all candidates
FeeAbout 270,incl.a270, incl. a 75 nonrefundable application fee (verify on danb.org)
RetakesUnlimited; one-time 33% reapplication discount

What Is on the DANB ICE Exam?

The DANB ICE exam delivers 75 multiple-choice questions in 60 minutes across four content domains. Prevention of Cross-contamination is the largest domain at 34%, followed by Process Instruments and Devices at 26%, with Prevention of Disease Transmission and Occupational Safety and Administration Protocols each contributing 20%.[2]

The full practice test below mirrors this official 20/34/26/20 blueprint, so the mix of questions you see matches the real exam.[3]

DANB ICE content domains
DomainWeightQuestionsWhat it covers
Prevention of Disease Transmission20%~15Modes of transmission, medical histories, hand hygiene, PPE selection and don/doff, aerosol and spatter control, dental dams, immunizations
Prevention of Cross-contamination34%~26Surface cleaning and disinfection, chemical disinfectants, surface barriers, tray setups, dental unit waterlines, evacuation lines, impression disinfection, waste disposal
Process Instruments and Devices26%~20Instrument transport and workflow, sterilization system selection, packaging and loading, sterility storage, monitoring and indicators, equipment malfunctions
Occupational Safety and Administration Protocols20%~14OSHA Bloodborne Pathogens and Hazard Communication standards, sharps safety, SDS, CDC guidelines, EPA/FDA roles, exposure control plans, logs and training records

Each domain carries its own published weight. The full DANB ICE practice test draws from a deep bank of realistic, explained questions stratified to these weights.[2]

DANB ICE domains — 75 questions
Prevention of Disease Transmission20% · ~15 questions
Prevention of Cross-contamination34% · ~26 questions
Process Instruments and Devices26% · ~20 questions
Occupational Safety and Administration Protocols20% · ~14 questions

Practice the DANB ICE by Domain

Take the full test from the Start Test button above, or target one domain at a time with the drills below. Each drill pulls from a deep bank of realistic, explained questions grounded in CDC and OSHA guidance.

DANB ICE Prevention of Disease Transmission Practice Test

Prevention of Disease Transmission is 20% of the exam.[2] It covers modes of disease transmission, occupational and patient risk, reviewing medical histories, and the core of Standard Precautions — hand hygiene (product types, technique, and when to use soap and water versus an alcohol-based rub), selecting and properly donning and doffing PPE, and minimizing aerosols, droplets, and spatter with barriers, dental dams, and high-volume evacuation.[4]

Use the Prevention of Disease Transmission drill to lock in hand-hygiene rules, PPE sequence, and aerosol control. The CDC names hand hygiene the single most important measure for reducing transmission, so these recurring topics decide a meaningful share of your ICE score.

DANB ICE Prevention of Cross-contamination Practice Test

Prevention of Cross-contamination is the largest domain at 34%.[2] It covers cleaning and disinfecting treatment areas and laboratories, preparing and using EPA-registered chemical disinfectants, surface barriers, tray setups (single-use devices and aseptic retrieval), maintaining and monitoring dental unit waterlines, cleaning evacuation lines and traps, disinfecting equipment and impressions, and disposing of biohazardous waste.[4]

Use the Prevention of Cross-contamination drill to master clinical-contact-surface asepsis, the dental unit waterline standard of less than or equal to 500 CFU/mL, and impression disinfection. Because this domain is a third of the exam, accuracy here moves your overall score the most.

DANB ICE Process Instruments and Devices Practice Test

Process Instruments and Devices is 26% of the exam.[2] It covers transporting contaminated instruments, one-directional workflow from dirty to clean, ultrasonic and chemical pre-cleaning, selecting the sterilization method, packaging and labeling, loading the sterilizer, and storing instruments to maintain sterility. It also covers monitoring — chemical and biological indicators, weekly spore testing with Geobacillus stearothermophilus, interpreting results, and responding to sterilization failures and equipment malfunctions.[4]

Use the Process Instruments and Devices drill to build accuracy on the Spaulding classification, sterilization monitoring, and what to do when a spore test or indicator fails. These concepts recur throughout the exam and on the job.

DANB ICE Occupational Safety and Administration Practice Test

Occupational Safety and Administration Protocols is 20% of the exam.[2] It covers the OSHA Bloodborne Pathogens Standard (engineering and work-practice controls, sharps safety, exposure and post-exposure protocols, hepatitis B vaccination, recordkeeping, and training)[5] and the OSHA Hazard Communication Standard (chemical hazards, safety data sheets, and secondary containers).[6] It also covers CDC guidelines, the roles of EPA and FDA, exposure control plans, sterilization logs, and training records.

Use the Occupational Safety and Administration drill to lock in OSHA requirements — the 10-working-day hepatitis B vaccine offer, sharps container specifications, SDS access, and the written exposure control plan reviewed at least annually. These regulatory details are frequently tested.

How Is the DANB ICE Scored?

The DANB ICE exam is scored on a 100–900 scale, with a scaled score of 400 or higher required to pass.[3] DANB uses computer-adaptive testing, so your score reflects the difficulty of the questions you answer correctly, not a raw percent; there is no penalty for guessing.

Each candidate is presented with the same percentage of questions from each domain, and the average candidate answers around half of the questions correctly. Pass the ICE and it counts toward your CDA, NELDA, or COA.

What Score Do You Need on the DANB ICE?

The passing standard is set by DANB: a scaled score of 400+ on a scale that runs from 100 to 900.[3] Because scoring is adaptive, focus on accuracy across all four domains rather than chasing a percent-correct.

Aim well above 400 so you pass with a buffer and avoid a retake. Drilling your weakest domain moves your overall result the most.

75
Questions
60 minutes
400+
Passing score
scale of 100–900
34%
Cross-contamination
largest domain

The takeaway: weight your prep toward Prevention of Cross-contamination, then shore up instrument processing, disease-transmission basics, and OSHA/CDC regulatory roles until you are consistently clearing 400 with room to spare.

What to Expect on Test Day

You can take the ICE exam in person at a test center or through remote online proctoring on your own computer with a webcam and microphone. Bring valid photo identification and arrive (or log on) early.

The exam is 75 multiple-choice questions in 60 minutes, computer-adaptive, and offered in English and Spanish. There are no eligibility requirements, and you may retake it as many times as needed.

Simulating the format with the practice test below makes the real exam feel routine.

How to Use This DANB ICE Practice Test

The ICE rewards broad review plus targeted domain work. Get the most from this practice test with these tips:

  • Diagnose, then drill. Take a full test first to find your weakest domain, then drill it until it clears 400.
  • Weight toward cross-contamination. It is a third of the exam, so master surface asepsis, barriers, waterlines, and impression disinfection.
  • Read every explanation. Understanding why an answer is right transfers to new questions on test day.
  • Think CDC and OSHA. The ICE is built on the CDC 2016 Summary of Infection Prevention Practices and OSHA 1910.1030 and 1910.1200 — study to those primary sources.
  • Lock in monitoring and sharps rules. Weekly spore testing, indicator failures, sharps containers, and the hepatitis B vaccine offer recur across the exam.

Conclusion

Passing the DANB ICE comes down to realistic, blueprint-weighted practice grounded in CDC and OSHA guidance. Take the full test to find your weak spots, drill Prevention of Disease Transmission, Prevention of Cross-contamination, Process Instruments and Devices, and Occupational Safety and Administration Protocols until each is solid, and build a comfortable buffer above 400.

This free DANB ICE practice test is how you get there.

DANB ICE Practice Test FAQ

The DANB Infection Control (ICE) exam has 75 multiple-choice questions with a 60-minute time limit. It is delivered by computer-adaptive testing, so each candidate sees the same percentage of questions from each content domain.

References

  1. 1.DANB. “Infection Control (ICE) Exam — 75 questions, 60 minutes, in-person or remote proctored; component of CDA, NELDA, and COA.” danb.org, 2026.
  2. 2.DANB. “Infection Control (ICE) Exam Outline and References (eff. 03/12/2025) — domains 20/34/26/20.” danb.org.
  3. 3.DANB. “4 Important Details to Know About DANB Exams (computer-adaptive, scored 100–900, 400 to pass).” danb.org.
  4. 4.CDC. “Summary of Infection Prevention Practices in Dental Settings: Basic Expectations for Safe Care (2016).” cdc.gov.
  5. 5.OSHA. “Bloodborne Pathogens Standard (1910.1030).” osha.gov.
  6. 6.OSHA. “Hazard Communication Standard (1910.1200).” osha.gov.
  7. 7.DANB. “Apply for DANB Exams (fees and reapplication).” danb.org.
Career Employer

Career Employer is the ultimate resource to help you get started working the job of your dreams. We cover topics from general career information, career searching, exam preparation with free study materials, career interviewing, and becoming successful in your career of choice.

Follow Us:

All Posts

Career Employer’s Editorial Process

Here at Career Employer, we focus a lot on providing factually accurate information that is always up to date. We strive to provide correct information using strict editorial processes, article editing, and fact-checking for all of the information found on our website. We only utilize trustworthy and relevant resources. To find out more, make sure to read our full editorial process page here.