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FREE Praxis General Science (5435) Study Guide 2026

Every Praxis General Science (5435) content category — Physical, Life, and Earth & Space Science — taught to the ETS exam, with worked examples, diagrams, built-in quizzes, and flashcards.

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This free Praxis General Science (5435) study guide teaches to the ETS Praxis General Science: Content Knowledge test — every content category the exam measures, organized the way ETS builds the test.[1] The 5435 is the licensure exam for prospective secondary general-science teachers, and it is broad rather than deep: it samples introductory physics, chemistry, biology, and earth and space science.

Because the test spans four categories, this guide covers all of them — the and of Physical Science, the cells, of Life Science, and the geology and of Earth and Space Science — plus the nature-of-science skills that thread through all of them. It’s interactive, not a wall of text: every category has a built-in checkpoint quiz, hover-able glossary terms, worked examples, and concept questions.

Read this guide category by category, test yourself at each checkpoint, then round out your free Praxis 5435 prep with our practice questions and flashcards.

Praxis 5435 is one of the 7 Praxis exams — explore our Praxis study guides to compare and prep across the whole family.

Praxis 5435 Exam Snapshot

Praxis General Science (5435) at a glance (2026)
DetailPraxis General Science (5435)
QuestionsAbout 135 selected-response questions
FormatComputer-delivered; single-answer and multiple-answer questions
Total time2 hours 30 minutes (150 minutes)
Score scale100–200 scaled score
Passing scoreSet by each state/agency (commonly ~141; varies — confirm yours)
Content categoriesNature & Impact of Science (~15%), Physical Science (~37%), Life Science (~26%), Earth & Space Science (~22%)
Tools providedOn-screen calculator and a list of constants/conversions
Who takes itProspective secondary general-science teachers
PublisherETS (Educational Testing Service)
Praxis General Science (5435) by content category (2026)
Physical Science
~37%~50 questions
Life Science
~26%~35 questions
Earth & Space Science
~22%~30 questions
Nature & Impact of Science & Engineering
~15%~20 questions

About 135 selected-response questions in 2.5 hours. Physical Science is the single biggest category — roughly a third of the test.

The four content categories are not weighted equally. Physical Scienceis the single biggest category — roughly a third of the test — so it deserves the most study time, followed by Life Science and Earth & Space Science.[1] Spread your work across all four, but lead with the categories that carry the most questions:

Praxis 5435 content categories (2026 approximate shares)
Physical Science37% · ~50 questions
Life Science26% · ~35 questions
Earth & Space Science22% · ~30 questions
Nature & Impact of Science & Engineering15% · ~20 questions

ETS reports the number of questions in each category, which we have expressed as approximate percentages of the roughly 135 total.[1]This guide teaches all four categories as four study modules, starting with the broad nature-of-science skills and then moving through Physical, Life, and Earth & Space Science.

1 · Nature & Impact of Science & Engineering

About 15% of the test (~20 questions). This category is about how science works — designing experiments, measuring and interpreting data, and the relationship among science, engineering, technology, and society.[1]

Scientific Method & Experiments

A controlled experiment changes one and measures its effect on a , while holding every other factor constant and including a for comparison. A good is testable and falsifiable — there must be a way to prove it wrong.

The scientific method — an iterative loop

Conclusions feed new questions, so the process cycles rather than ending — that is what makes science self-correcting.

  1. 1. Ask a questionObserve something and pose a testable question about it.
  2. 2. Form a hypothesisPropose a falsifiable explanation, often an 'if/then' prediction.
  3. 3. Design an experimentChange one independent variable; hold all others constant; include a control group.
  4. 4. Collect & analyze dataMeasure the dependent variable; look for patterns, accounting for error.
  5. 5. Draw a conclusionDecide whether the data support or refute the hypothesis.

New questions ↺ — a conclusion usually leads back to step 1 with a refined question.

Measurement, Accuracy & Error

is closeness to the true value; is closeness of repeated readings to each other. A miscalibrated balance that always reads high is precise but inaccurate — that is a systematic error. Random error scatters readings and is reduced by averaging trials.

Accuracy vs. precision vs. error type
TermWhat it means
AccurateClose to the true value
PreciseRepeated measurements close to each other (but maybe not to the truth)
Systematic errorA consistent shift in one direction — hurts accuracy; fix at the source
Random errorUnpredictable scatter — reduced by averaging many trials
SI base unitsMeter, kilogram, second, kelvin, ampere, mole, candela

Engineering, Technology & Society

Science seeks to understand the natural world; engineering applies that understanding to design solutions within real-world constraints such as cost, time, and safety. The engineering design process is iterative: define the problem, brainstorm, prototype, test, and redesign. Scientific and technological advances reshape society and raise ethical and environmental questions.

Checkpoint · Category 1 · Nature & Impact of Science

Question 1 of 10

In a well-designed experiment, what is the role of the independent variable?

2 · Physical Science

About 37% of the test (~50 questions) — the single biggest category. Physical Science is chemistry and physics: atoms and the periodic table, bonding and reactions, and forces, energy, waves, electricity, and magnetism.[1]

Atoms & the Periodic Table

An atom has protons and neutrons in its nucleus and electrons around it. The (protons) defines the element; the mass number is protons plus neutrons. differ in neutrons, and an has gained or lost electrons. Elements in the same group share properties because they have the same number of valence electrons.

Periodic-table trends — direction of change
TrendRight → Left across a periodTop → Bottom down a group
Atomic radiusincreasesincreases
Ionization energydecreasesdecreases
Electronegativitydecreasesdecreases
Metallic characterincreasesincreases

Read across a period (a row) and down a group (a column). Atomic radius is the master trend — the others largely follow how tightly the nucleus holds the outer electrons.

Bonding, Reactions & Matter

An transfers electrons from a metal to a nonmetal; a shares electrons between nonmetals. Every reaction obeys , which is why chemical equations must be balanced. Acids donate H⁺ ions (pH below 7); bases accept them (pH above 7).

Forces, Motion & Energy

says net force equals mass times acceleration, F=ma F = ma . is KE=12mv2 KE = \tfrac{1}{2}mv^2 and gravitational potential energy is PE=mgh PE = mgh . By the , energy only changes form — it is never lost.

Waves, Electricity & Magnetism

Wave speed is v=fλ v = f\lambda (frequency times wavelength). The runs from radio (low energy) to gamma rays (high energy).[4] In circuits, Ohm’s law is V=IR V = IR ; in a series circuit current is the same everywhere, while in a parallel circuit voltage is the same across branches.

Core Physical Science relationships
QuantityRelationship
Newton's second lawF=ma F = ma
Densityρ=mV \rho = \dfrac{m}{V}
Kinetic energyKE=12mv2 KE = \tfrac{1}{2}mv^2
Wave speedv=fλ v = f\lambda
Ohm's lawV=IR V = IR

Checkpoint · Category 2 · Physical Science

Question 1 of 10

What three subatomic particles make up a neutral atom, and where is most of its mass located?

3 · Life Science

About 26% of the test (~35 questions). Life Science covers cells and their energy processes, genetics and heredity, evolution and classification, and ecology.[1]

Cells & Energy (Photosynthesis & Respiration)

says all living things are made of cells that come from pre-existing cells. in the chloroplast stores light energy in glucose, and in the mitochondria releases it as — the two are nearly reverse processes.

Photosynthesis and cellular respiration — reverse processes
Photosynthesis (chloroplast)6 CO₂ + 6 H₂O + light → C₆H₁₂O₆ + 6 O₂. Stores light energy in glucose.
Cellular respiration (mitochondria)C₆H₁₂O₆ + 6 O₂ → 6 CO₂ + 6 H₂O + ATP. Releases that stored energy.

The products of one are the reactants of the other — oxygen and glucose cycle between plants and all respiring cells, balancing carbon and energy in living systems.

Genetics & Heredity

DNA stores genetic information in base pairs (A-T, G-C). A is expressed when present; a recessive allele only shows with two copies. A Punnett square predicts offspring ratios. makes two identical cells for growth; makes four varied gametes for reproduction.

Evolution & Classification

drives evolution: individuals with traits better suited to their environment survive and reproduce more, shifting a population over generations.[6] Mutation supplies the variation selection acts on. Organisms are classified in the order Domain, Kingdom, Phylum, Class, Order, Family, Genus, Species.

Ecology & Ecosystems

Energy flows one way through a food web: producers capture sunlight, consumers eat them, and decomposers recycle nutrients — with only about 10% of energy passing to each higher level. Matter, by contrast, cycles (the carbon, nitrogen, and water cycles).

Checkpoint · Category 3 · Life Science

Question 1 of 10

What is the overall purpose of photosynthesis in green plants?

4 · Earth & Space Science

About 22% of the test (~30 questions).Earth and Space Science covers Earth’s structure and plate tectonics, rocks and geologic time, the atmosphere and weather, and basic astronomy.[1]

Earth’s Structure & Plate Tectonics

Earth’s layers, from outside in, are crust, mantle, liquid outer core, and solid inner core. explains how mantle convection moves the plates, producing earthquakes, volcanoes, and mountains along their boundaries.[5]

Three types of plate boundary
DivergentPlates pull apartNew crust forms; mid-ocean ridges and rift valleys.
ConvergentPlates collideSubduction; volcanoes, mountains, deep trenches.
TransformPlates slide pastEarthquakes (e.g., San Andreas Fault).

Mantle convection drives all three. Most earthquakes and volcanoes cluster along these boundaries.

Rocks, Minerals & Geologic Time

The three rock types — , , and — continuously transform through the rock cycle. Fossils form mostly in sedimentary rock, and the says deeper layers are older.

The rock cycle
  1. Igneous rockCooling & solidifying of magma or lava
  2. Sedimentary rockWeathering, then compaction & cementation of sediments
  3. Metamorphic rockHeat & pressure transform existing rock

Any rock can become any other: melting forms igneous, weathering and burial form sedimentary, and heat and pressure form metamorphic — continuously, over geologic time.

Atmosphere, Weather & Water

The atmosphere layers (troposphere, stratosphere with its ozone, mesosphere, thermosphere) surround Earth. The water cycle moves water through evaporation, condensation, and precipitation, and the traps heat that keeps Earth warm — with excess gas intensifying it. Weather is short-term; climate is the long-term average.

Astronomy & the Solar System

The eight planets orbit the Sun, a star powered by nuclear fusion. Earth’s daily rotation causes day and night, while its yearly revolution and the 23.5° axial tilt cause the seasons — not its distance from the Sun.[7] Moon phases and eclipses come from the Sun-Earth-Moon geometry.

Checkpoint · Category 4 · Earth & Space Science

Question 1 of 10

Which layer of Earth lies directly beneath the crust and behaves as a slowly flowing solid that drives the movement of tectonic plates?

How to Use This Study Guide

A study guide is a map, not the whole territory — use it alongside the official ETS materials and our free tools. Because the 5435 is broad, the goal is even coverage across all four categories, so spaced, mixed practice beats one long cram. Lead with Physical Science (the biggest category), and give extra time to whichever science you studied least in school.

A study loop that actually works
  1. 1

    Read a category here

    Work through one content category at a time — start with Physical Science, the heaviest.

  2. 2

    Take the checkpoint

    The quick check at the end of each category exposes what didn't stick.

  3. 3

    Drill the gaps

    Send your weak category straight into the free practice questions and flashcards.

  4. 4

    Take full, timed practice

    Sit a full practice test to build stamina across all four categories, then review every miss.

Praxis 5435 Concept Questions

Common science concepts the Praxis 5435 actually measures — at least one per content category. Tap any card for a short, exam-ready answer backed by an authoritative source (ETS, NASA, USGS, and the NIH), then test yourself on them as flashcards.

Praxis 5435 Glossary

Quick definitions for the terms you’ll see most across the Praxis General Science (5435):

Accuracy
How close a measurement is to the true value. Distinct from precision, which is how close repeated measurements are to each other.
Atomic number
The number of protons in an atom, which defines the element's identity.
ATP
Adenosine triphosphate — the cell's main energy-carrying molecule, produced by cellular respiration.
Cell theory
The principle that all living things are made of cells, the cell is the basic unit of life, and all cells come from pre-existing cells.
Cellular respiration
The process by which cells break down glucose with oxygen to release energy as ATP, mainly in the mitochondria.
Conservation of energy
Energy cannot be created or destroyed, only transformed; the total energy of a closed system stays constant.
Conservation of mass
The principle that mass is neither created nor destroyed in a chemical reaction, so reactant mass equals product mass.
Control group
The group in an experiment that does not receive the treatment, providing a baseline for comparison.
Covalent bond
A chemical bond formed when two nonmetal atoms share electrons.
Dependent variable
The outcome measured in an experiment; it responds to (depends on) the independent variable and is plotted on the y-axis.
Dominant allele
A version of a gene that is expressed whenever it is present, masking a recessive allele.
Electromagnetic spectrum
The full range of electromagnetic waves — radio, microwave, infrared, visible, ultraviolet, X-ray, gamma — ordered by frequency and energy.
Electronegativity
A measure of an atom's tendency to attract bonding electrons; it increases up and to the right on the periodic table, peaking at fluorine.
Greenhouse effect
The warming of Earth's surface when atmospheric gases such as carbon dioxide and water vapor trap heat radiating from the surface.
Hypothesis
A testable, falsifiable proposed explanation, often stated as an 'if/then' prediction about how variables relate.
Igneous rock
Rock formed from the cooling and solidifying of molten magma or lava.
Independent variable
The factor a researcher deliberately changes in an experiment to test its effect; it is plotted on the x-axis.
Ion
An atom that has gained or lost electrons, giving it a net negative or positive charge.
Ionic bond
A bond formed by the transfer of electrons from a metal to a nonmetal, creating oppositely charged ions that attract.
Isotope
An atom of an element with the same number of protons but a different number of neutrons, giving it a different mass number.
Kinetic energy
The energy of motion, equal to one-half mass times velocity squared (KE = ½mv²); it grows with the square of speed.
Law of superposition
In undisturbed rock layers, the oldest layers lie at the bottom and the youngest at the top.
Meiosis
Cell division producing four genetically varied haploid gametes with half the chromosome number.
Metamorphic rock
Rock formed when existing rock is transformed by heat and pressure, such as marble from limestone.
Mitosis
Cell division producing two genetically identical diploid cells, used for growth and repair.
Natural selection
The process by which individuals with traits better suited to their environment survive and reproduce more, shifting a population's traits over generations.
Newton's second law
The net force on an object equals its mass times its acceleration, written F = ma.
Photosynthesis
The process by which plants use light energy to convert carbon dioxide and water into glucose and oxygen, in the chloroplast.
Plate tectonics
The theory that Earth's rigid outer shell is broken into plates that slowly move over the softer mantle, driven by convection.
Precision
How close repeated measurements are to one another. Measurements can be precise but inaccurate if a systematic error shifts them all.
Scientific theory
A broad, well-substantiated explanation supported by a large body of evidence, such as evolution or plate tectonics — far stronger than a guess.
Sedimentary rock
Rock formed when sediments are compacted and cemented over time; it often contains fossils.

Free Praxis 5435 Study Materials & Resources

Everything you need to prepare for the Praxis General Science (5435) is free here — no paywall, no sign-up. This guide is the foundation; pair it with the rest of our free Praxis 5435 study materials for active recall, timed practice, and last-minute review:

Praxis 5435 Study Guide FAQ

The Praxis General Science: Content Knowledge (5435) test has about 135 selected-response questions and a total testing time of 2.5 hours. The questions are drawn from four content categories: Nature and Impact of Science and Engineering, Physical Science, Life Science, and Earth and Space Science.

References

  1. 1.ETS. “Praxis General Science: Content Knowledge (5435) — Test Overview.” ETS.
  2. 2.ETS. “About The Praxis Tests.” ETS.
  3. 3.ETS. “Praxis Tests — Understanding Your Praxis Scores.” ETS.
  4. 4.NASA Science. “Introduction to the Electromagnetic Spectrum.” NASA.
  5. 5.U.S. Geological Survey. “Understanding Plate Motions.” USGS.
  6. 6.National Human Genome Research Institute. “Evolution — Genetics Glossary.” NHGRI.
  7. 7.NASA Space Place. “What Causes the Seasons?.” NASA.

Sources for the concept answers

Every answer in the Praxis 5435 concept questions above is drawn from an official or authoritative primary source:

  1. National Institute of General Medical Sciences. “Cells: The Basic Units of Life.” National Institute of General Medical Sciences.
  2. National Human Genome Research Institute. “Genetics Glossary — Allele.” National Human Genome Research Institute.
  3. NOAA. “Food Webs and the Ocean.” NOAA.
  4. U.S. Geological Survey. “Rock Cycle.” U.S. Geological Survey.
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