PTCB Domain 1: Medications Welcome to your PTCB Domain 1: Medications 1. PTCB: Medications Which of the following medications is a non-selective Beta-Adrenergic Antagonist used primarily for the management of hypertension, angina, and arrhythmias? A. Metoprolol B. Atenolol C. Propranolol D. Esmolol None 2. PTCB: Medications In the context of anticoagulant therapy, which of the following is the antidote for Warfarin? A. Vitamin K B. Protamine sulfate C. Naloxone D. Flumazenil None 3. PTCB: Medications Which antiepileptic drug requires genetic testing prior to initiation due to a risk of severe skin reactions in patients with the HLA-B*1502 allele? A. Phenytoin B. Carbamazepine C. Valproate D. Lamotrigine None 4. PTCB: Medications A patient with atrial fibrillation is most likely to be prescribed which medication to prevent stroke? A. Warfarin B. Lisinopril C. Amlodipine D. Furosemide None 5. PTCB: Medications Which medication is considered a first-line treatment for heart failure with reduced ejection fraction (HFrEF)? A. Digoxin B. Furosemide C. Enalapril D. Atenolol None 6. PTCB: Medications What is the mechanism of action of Allopurinol in the treatment of gout? A. Increases uric acid excretion B. Inhibits xanthine oxidase C. Blocks tubular reabsorption of uric acid D. Inhibits cyclooxygenase None 7. PTCB: Medications Which medication is primarily used as a thrombolytic agent in the management of acute myocardial infarction? A. Enoxaparin B. Clopidogrel C. Alteplase D. Atorvastatin None 8. PTCB: Medications In the management of Type 2 Diabetes Mellitus, which medication works by inhibiting the DPP-4 enzyme, thereby increasing incretin levels? A. Metformin B. Sitagliptin C. Pioglitazone D. Glipizide None 9. PTCB: Medications Which medication is indicated for the prophylaxis of migraine headaches and works by modulating serotonergic and other neurotransmitter systems? A. Sumatriptan B. Propranolol C. Topiramate D. Amitriptyline None 10. PTCB: Medications A patient with COPD is likely to be prescribed which class of medication for maintenance therapy? A. ACE inhibitors B. Beta-agonists C. Calcium channel blockers D. NSAIDs None 11. PTCB: Medications What is the primary action of Aprepitant when used as part of antiemetic therapy in patients undergoing chemotherapy? A. Blocks dopamine receptors B. Inhibits histamine release C. Blocks serotonin receptors D. Blocks neurokinin 1 (NK1) receptors None 12. PTCB: Medications Which of the following medications is an antiretroviral agent that inhibits the CCR5 co-receptor, preventing HIV entry into cells? A. Zidovudine B. Ritonavir C. Maraviroc D. Efavirenz None 13. PTCB: Medications Which of the following is a monoclonal antibody used for the treatment of osteoporosis by inhibiting osteoclast-mediated bone resorption? A. Alendronate B. Calcitonin C. Denosumab D. Teriparatide None 14. PTCB: Medications What is the primary function of Sofosbuvir in the treatment regimen of Hepatitis C Virus (HCV) infection? A. Protease inhibitor B. Neuraminidase inhibitor C. Nucleotide analog NS5B polymerase inhibitor D. Immune modulator None 15. PTCB: Medications Which medication, used in the management of Multiple Sclerosis (MS), functions by trapping immune cells in lymph nodes, preventing them from crossing the blood-brain barrier? A. Interferon beta-1a B. Glatiramer acetate C. Fingolimod D. Natalizumab None 16. PTCB: Medications In the treatment of chronic myeloid leukemia (CML), which medication targets the BCR-ABL tyrosine kinase created by the Philadelphia chromosome? A. Cyclophosphamide B. Imatinib C. Vincristine D. Rituximab None 17. PTCB: Medications Which of the following is an oral antidiabetic agent that works by inhibiting the sodium-glucose co-transporter 2 (SGLT2) in the kidneys? A. Glimepiride B. Metformin C. Canagliflozin D. Repaglinide None 18. PTCB: Medications A patient on antipsychotic therapy experiencing extrapyramidal side effects (EPS) may benefit from the administration of which of the following medications? A. Haloperidol B. Clozapine C. Lorazepam D. Benztropine None 19. PTCB: Medications In the context of chemotherapy, what is the mechanism of action of Methotrexate? A. Alkylating agent B. Topoisomerase inhibitor C. Antimetabolite inhibiting dihydrofolate reductase D. Microtubule inhibitor None 20. PTCB: Medications Which of the following inhalational anesthetics is known for its minimal effect on the cardiovascular system, making it suitable for patients with cardiac risk factors? A. Isoflurane B. Sevoflurane C. Desflurane D. Nitrous oxide None 21. PTCB: Medications What is the primary clinical use of Rituximab, a monoclonal antibody? A. To promote angiogenesis in wound healing B. To reduce cholesterol levels in hyperlipidemia C. To target CD20+ B cells in certain autoimmune diseases and cancers D. To inhibit platelet aggregation in thrombotic disorders None 22. PTCB: Medications Which of the following medications acts as an inhibitor of the HMG-CoA reductase enzyme, playing a crucial role in the management of hyperlipidemia? A. Fenofibrate B. Ezetimibe C. Atorvastatin D. Niacin None 23. PTCB: Medications In the treatment of Bipolar Disorder, which of the following medications is classified as a mood stabilizer and also acts on the inositol triphosphate pathway? A. Lithium B. Olanzapine C. Sertraline D. Valproate None 24. PTCB: Medications Which antibiotic is known for its effectiveness against MRSA and works by inhibiting bacterial protein synthesis at the 50S ribosomal subunit? A. Cephalexin B. Vancomycin C. Linezolid D. Meropenem None 25. PTCB: Medications What is the primary mechanism of action of Tamsulosin used in the management of benign prostatic hyperplasia (BPH)? A. 5-alpha-reductase inhibitor B. Alpha-1 adrenergic receptor antagonist C. Phosphodiesterase type 5 inhibitor D. Muscarinic receptor antagonist None 26. PTCB: Medications For the management of acute migraine headaches, which medication functions as a serotonin (5-HT1) receptor agonist, causing vasoconstriction of intracranial blood vessels? A. Ibuprofen B. Acetaminophen C. Sumatriptan D. Amitriptyline None 27. PTCB: Medications Which antidiabetic medication class does Empagliflozin belong to, known for reducing glucose reabsorption in the kidneys by inhibiting SGLT2? A. Sulfonylureas B. DPP-4 inhibitors C. GLP-1 receptor agonists D. SGLT2 inhibitors None 28. PTCB: Medications Which medication is used as a last resort in patients with multidrug-resistant tuberculosis 'MDR-TB' and functions by inhibiting mycolic acid synthesis? A. Isoniazid B. Rifampin C. Bedaquiline D. Ethambutol None 29. PTCB: Medications What is the role of Dabigatran in anticoagulant therapy? A. Vitamin K antagonist B. Direct thrombin inhibitor C. Factor Xa inhibitor D. ADP receptor inhibitor None 30. PTCB: Medications Which of the following is a phosphodiesterase inhibitor used in the management of Chronic Obstructive Pulmonary Disease 'COPD' to decrease inflammation and relax airway smooth muscles? A. Theophylline B. Ipratropium C. Beclomethasone D. Albuterol None 31. PTCB: Medications Which of the following medications is used as an adjunct in the treatment of partial seizures and operates by modulating synaptic release of glutamate through an effect on SV2A proteins? A. Carbamazepine B. Levetiracetam C. Phenobarbital D. Diazepam None 32. PTCB: Medications In the setting of anticoagulation for atrial fibrillation, which of the following medications functions as a direct Factor Xa inhibitor? A. Warfarin B. Dabigatran C. Rivaroxaban D. Enoxaparin None 33. PTCB: Medications Which medication, indicated for the treatment of Chronic Hepatitis B infection, is a nucleoside analogue that inhibits viral DNA polymerase? A. Ribavirin B. Sofosbuvir C. Tenofovir D. Simeprevir None 34. PTCB: Medications A medication used to prevent organ transplant rejection that inhibits calcineurin, thereby reducing IL-2 production and T-cell activation is: A. Mycophenolate mofetil B. Azathioprine C. Tacrolimus D. Methotrexate None 35. PTCB: Medications What is the mechanism of action of Prazosin when used in the management of hypertension? A. Alpha-1 adrenergic receptor antagonist B. Beta-adrenergic receptor antagonist C. Calcium channel blocker D. Angiotensin II receptor blocker None 36. PTCB: Medications Which of the following is an anti-VEGF (Vascular Endothelial Growth Factor) medication used in the treatment of wet age-related macular degeneration 'AMD'? A. Ranibizumab B. Timolol C. Ketorolac D. Cyclosporine None 37. PTCB: Medications A patient diagnosed with Clostridium difficile infection is likely to benefit from which of the following antibiotics, known for its specificity to the gut and minimal systemic absorption? A. Metronidazole B. Vancomycin administered orally C. Ciprofloxacin D. Amoxicillin None 38. PTCB: Medications What is the mechanism of action of Allopurinol in the treatment of gout? A. Increases uric acid excretion B. Inhibits xanthine oxidase C. Blocks tubular reabsorption of uric acid D. Inhibits cyclooxygenase None 39. PTCB: Medications Which medication, used in the management of Multiple Sclerosis (MS), functions by trapping immune cells in lymph nodes, preventing them from crossing the blood-brain barrier? A. Interferon beta-1a B. Glatiramer acetate C. Fingolimod D. Natalizumab None 40. PTCB: Medications Which of the following is a phosphodiesterase inhibitor used in the management of Chronic Obstructive Pulmonary Disease 'COPD' to decrease inflammation and relax airway smooth muscles? A. Theophylline B. Ipratropium C. Beclomethasone D. Albuterol None 1 out of 40 Time is Up! Time's up