HESI A2: Reading Comprehension (Quiz 5)

A team led by Massachusetts General Hospital produced premature cells that support early heart development. These scientists hope to use patient cells to generate functioning heart tissue. If they are successful, the cells could revolutionize transplants in treating heart failure. Pre-epicardial cells form the epicardium, a membrane covering the heart’s outer surface. These cells are central in supporting heart development in utero. Mature cells from the skin, for instance, can be reprogrammed into embryo-like stem cells. When heart muscle cells contact pre-epicardial cells, they develop into vital epicardial cells to support embryonic heart formation. A single blood draw can help retrace early heart development stages, but the more advanced heart structure is highly complex. The findings may eventually contribute to new heart failure therapies. What is the best summary of the passage?

Does Low Body Temperature Cause Illness?: As children, we are often told to dress warmly in the winter so we do not get sick. This is a common piece of advice, but is there any truth behind it? In fact, there is no scientific evidence to suggest that being cold can get you sick. Most illnesses are caused by viruses and bacteria. Illnesses like strep throat, influenza, and the common cold are only spread through contact with other infected people. How cold you are when you come into contact with the virus or bacteria has nothing to do with whether or not you will get sick. The effect of body temperature on contracting illness was tested on human beings in the 1950s. Researchers divided volunteers into two groups: half of them were kept in a warm room and the other half were kept in a cold room. Both groups were then exposed to rhinovirus–the virus responsible for the common cold. The researchers discovered that members of both groups developed colds at the same rate. Since that first experiment, there have been similar experiments performed with a variety of different illnesses. All have yielded the same result: being cold does not make a person more likely to get sick. Of course, it does seem that people do get sick more often when the weather is cold. However, this is because there is some evidence that people do get sick more often in cold weather, but it has nothing to do with forgetting to bundle up when it is chilly. When it is cold outside, people tend to stay inside. With so many people gathered closely together indoors, germs are spread more easily. Germs are spread from person to person, regardless of how cold or warm their bodies are. Which detail in the text supports the idea that people get sick more often when it is cold outside?

Fibromyalgia: Fibromyalgia is a chronic condition that affects an estimated 3-6% of the world’s population. The disorder is characterized by both physiological and psychological symptoms, including nerve pain, fatigue, sleep and mood disturbances, headaches, bowel problems, and incontinence. The exact cause of fibromyalgia is unknown. For some people, fibromyalgia symptoms begin after some sort of physical or psychological stress. However, for others, the onset of symptoms is gradual. Research has shown that genetics may play a part, but there is also evidence that environmental factors can contribute. The wide variety of symptoms made it difficult to diagnose and treat for many years, though recent research has made some promising advances. Although a cure for fibromyalgia has not yet been developed, research has shown that some of the symptoms can be treated with pharmaceuticals, such as tricyclics or gabapentinoids, or non-pharmacological methods, such as meditation, mindfulness, and cognitive behavior therapy. The most successful pharmacological treatment for fibromyalgia has been tricyclic antidepressants, such as amitriptyline and nortriptyline. These drugs increase the levels of the neurotransmitters serotonin and norepinephrine, which are often found at decreased levels in the brains of people who suffer from chronic pain. By boosting endorphins and relaxing muscles, tricyclics can ease some of the musculoskeletal pain felt by people with fibromyalgia. Question: Which of the following can be inferred from information in the passage?

GMOs: GMOs, or genetically modified organisms, are organisms whose genes have been altered in laboratories. Scientists modify the genetic codes of plants or animals by inserting copies of desirable genes into the organism’s DNA. While modifying organisms in a laboratory is a relatively new scientific development, people have been experimenting with genetics on plants and animals for centuries. For example, cattle ranchers have selectively bred their animals to produce cows that give more milk. Although some people fear the “Frankenstein” nature of GMOs, there is no scientific evidence to suggest that GMO-based foods are harmful for human consumption. In fact, there are several reasons to believe that GMOs are actually quite beneficial. Through genetic modification, scientists can breed species of plants or animals that yield hardier, more abundant, or even more nutritious food. Geneticists have been able to produce rice plants that can survive droughts and wheat plants that are naturally pest-resistant. Some genetically modified foods have been engineered to have higher levels of specific nutrients, such as protein or calcium. Proponents of GMOs argue that these kinds of advances might one day help to end world hunger. Furthermore, genetically modified crops and animals can be bred to require fewer natural resources and produce less waste. This means that GMOs might also be better for the environment. Question: What is the main idea of the passage?

Mercury in Fish: Mercury is a highly toxic metal found in neon signs, fluorescent lights, older thermometers, and certain kinds of telescopes. It can also be found in something that many people eat on a regular basis: fish. The mercury we might find in a can of tuna is most likely an indirect result of the coal industry. Mercury, which is naturally found in coal, is released into the air when coal is burned. It finds its way into waterways via mercury-laced rain. Mercury accumulates in certain kinds of fish through a process called biomagnification. Biomagnification occurs when a substance enters the food chain in small amounts at the very bottom and then increases in concentration in animals higher up on the food chain. Once a fish eats another creature containing mercury, the mercury does not leave that fish’s body, but instead is stored in fat. Therefore, the mercury continually accumulates as more mercury-contaminated fish are eaten. Despite the toxicity of mercury and the widespread nature of fish contamination, there is no need for the public to be overly apprehensive. Many popular fish, such as salmon, catfish, or tilapia, are generally safe to eat. Other fish, especially tuna and grouper, should only be eaten in moderation. Young children and pregnant women should be especially cautious about how many servings of mercury-contaminated fish they have per week. It is recommended that people in these groups not eat more than 2 servings of mercury-contaminated fish per week. Fish with the highest levels of mercury include shark, swordfish, and king mackerel. All people should avoid eating large amounts of these kinds of fish, and no one should eat these fish more frequently than once a month. Question: Which supporting detail is an example of a suggestion, rather than factual information?

Wrinkles: Skin wrinkles are caused by a variety of factors. Some of these factors are intrinsic, meaning that you cannot control them because they occur naturally. Others are extrinsic, meaning that they are caused by circumstances outside of the body. One intrinsic factor is aging. As you age, your skin loses collagen, which is the protein responsible for keeping your skin elastic. With less collagen, your skin becomes thinner and more fragile. Aging also reduces the functioning of sweat and oil glands, which work to keep the skin looking smooth. You also lose fat in the deeper layers of your skin as you age. This fat loss causes your skin to sag and develop deeper wrinkles. The two most common extrinsic factors are exposure to ultraviolet radiation (UV rays) and smoking. UV rays in sunlight break down your skin’s connective tissue and collagen fibers. To prevent the appearance of wrinkles (as well as protect yourself from skin cancer), you should always use UV-blocking sunscreen. The nicotine in cigarettes is the most likely link between smoking and wrinkles. Nicotine narrows the blood vessels, reducing the blood supply to your skin tissue. This deprives your skin of oxygen and important nutrients, causing damage that contributes to wrinkles. Question: Why does the author include information regarding UV-blocking sunscreen?

Social media has highlighted increasingly ridiculous ‘gender reveal’ parties and theatrics. But to some degree, it’s understandable that parents-to-be are eager to find out: boy or girl? A Newcastle University study might help solve the mystery. Researchers collected data from 927 family trees from North America and Europe spanning back to 1600 including information on 556,387 people total. Women only have X chromosomes, whereas men have X and Y chromosomes to pass on. So the sex of a baby is determined by whether the man contributes an X, making a girl (XX), or a Y to make a boy (XY). The study discovered that a male gene determines whether men have more X or Y chromosomes to pass on. Men with brothers are more likely to have sons, and men with sisters are more likely to have daughters. Which of the following conclusions can be drawn about what determines the sex of a baby?

Does Low Body Temperature Cause Illness?: As children, we are often told to dress warmly in the winter so we do not get sick. This is a common piece of advice, but is there any truth behind it? In fact, there is no scientific evidence to suggest that being cold can get you sick. Most illnesses are caused by viruses and bacteria. Illnesses like strep throat, influenza, and the common cold are only spread through contact with other infected people. How cold you are when you come into contact with the virus or bacteria has nothing to do with whether or not you will get sick. The effect of body temperature on contracting illness was tested on human beings in the 1950s. Researchers divided volunteers into two groups: half of them were kept in a warm room and the other half were kept in a cold room. Both groups were then exposed to rhinovirus–the virus responsible for the common cold. The researchers discovered that members of both groups developed colds at the same rate. Since that first experiment, there have been similar experiments performed with a variety of different illnesses. All have yielded the same result: being cold does not make a person more likely to get sick. Of course, it does seem that people do get sick more often when the weather is cold. However, this is because there is some evidence that people do get sick more often in cold weather, but it has nothing to do with forgetting to bundle up when it is chilly. When it is cold outside, people tend to stay inside. With so many people gathered closely together indoors, germs are spread more easily. Germs are spread from person to person, regardless of how cold or warm their bodies are. What is the main idea of the passage?

Mercury in Fish: Mercury is a highly toxic metal found in neon signs, fluorescent lights, older thermometers, and certain kinds of telescopes. It can also be found in something that many people eat on a regular basis: fish. The mercury we might find in a can of tuna is most likely an indirect result of the coal industry. Mercury, which is naturally found in coal, is released into the air when coal is burned. It finds its way into waterways via mercury-laced rain. Mercury accumulates in certain kinds of fish through a process called biomagnification. Biomagnification occurs when a substance enters the food chain in small amounts at the very bottom and then increases in concentration in animals higher up on the food chain. Once a fish eats another creature containing mercury, the mercury does not leave that fish’s body but instead is stored in fat. Therefore, the mercury continually accumulates as more mercury-contaminated fish are eaten. Despite the toxicity of mercury and the widespread nature of fish contamination, there is no need for the public to be overly apprehensive. Many popular fish, such as salmon, catfish, or tilapia, are generally safe to eat. Other fish, especially tuna and grouper, should only be eaten in moderation. Young children and pregnant women should be especially cautious about how many servings of mercury-contaminated fish they have per week. It is recommended that people in these groups not eat more than 2 servings of mercury-contaminated fish per week. Fish with the highest levels of mercury include shark, swordfish, and king mackerel. All people should avoid eating large amounts of these kinds of fish, and no one should eat these fish more frequently than once a month. Why does the author include the detail regarding the coal industry in the first paragraph?

In the 17th and 18th centuries, Antonio Stradivari and Giuseppe Guarneri crafted the world’s most famous violins. The antiques are still fiercely sought after among musicians. A recent discovery uncovers chemical treatments that make the instruments superior. The uncommonly thin soundboards, key components in sound production, were subject to proprietary chemical treatments. Texas A&M biochemist Nagyvary stated that “special salts they used for [impregnating]… the wood” were responsible for both “acoustical advantages” and “mechanical strength.” Scientists used spectroscopy (light and radiation), microscopic analysis, and chemical techniques to identify chemicals. They found zinc and copper sulfates, borax, lime water, and alum. Since the time of ancient Egyptians, people have used borax as a preservative. The chemical mix was not just applied to the surface of the violins’ wood-, Stradivari and Guarneri soaked the spruce planks in it. What is the best summary of the passage?

Wrinkles: Skin wrinkles are caused by a variety of factors. Some of these factors are intrinsic, meaning that you cannot control them because they occur naturally. Others are extrinsic, meaning that they are caused by circumstances outside of the body. One intrinsic factor is aging. As you age, your skin loses collagen, which is the protein responsible for keeping your skin elastic. With less collagen, your skin becomes thinner and more fragile. Aging also reduces the functioning of sweat and oil glands, which work to keep the skin looking smooth. You also lose fat in the deeper layers of your skin as you age. This fat loss causes your skin to sag and develop deeper wrinkles. The two most common extrinsic factors are exposure to ultraviolet radiation (UV rays) and smoking. UV rays in sunlight break down your skin’s connective tissue and collagen fibers. To prevent the appearance of wrinkles (as well as protect yourself from skin cancer), you should always use UV-blocking sunscreen. The nicotine in cigarettes is the most likely link between smoking and wrinkles. Nicotine narrows the blood vessels, reducing the blood supply to your skin tissue. This deprives your skin of oxygen and important nutrients, causing damage that contributes to wrinkles. Question: Why does the author include the detail “nicotine narrows the blood vessels” in paragraph 3?

Fibromyalgia: Fibromyalgia is a chronic condition that affects an estimated 3-6% of the world’s population. The disorder is characterized by both physiological and psychological symptoms, including nerve pain, fatigue, sleep and mood disturbances, headaches, bowel problems, and incontinence. The exact cause of fibromyalgia is unknown. For some people, fibromyalgia symptoms begin after some sort of physical or psychological stress. However, for others, the onset of symptoms is gradual. Research has shown that genetics may play a part, but there is also evidence that environmental factors can contribute. The wide variety of symptoms made it difficult to diagnose and treat for many years, though recent research has made some promising advances. Although a cure for fibromyalgia has not yet been developed, research has shown that some of the symptoms can be treated with pharmaceuticals, such as tricyclics or gabapentinoids, or non-pharmacological methods, such as meditation, mindfulness, and cognitive behavior therapy. The most successful pharmacological treatment for fibromyalgia has been tricyclic antidepressants, such as amitriptyline and nortriptyline. These drugs increase the levels of the neurotransmitters serotonin and norepinephrine, which are often found at decreased levels in the brains of people who suffer from chronic pain. By boosting endorphins and relaxing muscles, tricyclics can ease some of the musculoskeletal pain felt by people with fibromyalgia. Question: Which of the following is true according to the passage?

Polystyrene is a common insulation and packaging plastic. Its bulk and low density make it unaffordable to recycle. Additionally, it contains an additive called HBCD (hexabromocyclododecane), a flame retardant. HBCD and similar plastics additives have been shown to have substantial environmental and health impacts including neurotoxicity and endocrine disruption. Mealworms can apparently eat these toxic plastics safely, according to a Stanford University study. Without experiencing negative effects, the mealworms can eat polystyrene that contains HBCD. The mealworms can then be used in protein-rich feed for other animals. The chemicals do not build up in the mealworms’ bodies. The microorganisms in their guts biodegrade the plastic, so they are still safe for shrimp, fish, snakes, and chickens to eat. What is the best summary of the passage?

Does Low Body Temperature Cause Illness?: As children, we are often told to dress warmly in the winter so we do not get sick. This is a common piece of advice, but is there any truth behind it? In fact, there is no scientific evidence to suggest that being cold can get you sick. Most illnesses are caused by viruses and bacteria. Illnesses like strep throat, influenza, and the common cold are only spread through contact with other infected people. How cold you are when you come into contact with the virus or bacteria has nothing to do with whether or not you will get sick. The effect of body temperature on contracting illness was tested on human beings in the 1950s. Researchers divided volunteers into two groups: half of them were kept in a warm room and the other half were kept in a cold room. Both groups were then exposed to rhinovirus–the virus responsible for the common cold. The researchers discovered that members of both groups developed colds at the same rate. Since that first experiment, there have been similar experiments performed with a variety of different illnesses. All have yielded the same result: being cold does not make a person more likely to get sick. Of course, it does seem that people do get sick more often when the weather is cold. However, this is because there is some evidence that people do get sick more often in cold weather, but it has nothing to do with forgetting to bundle up when it is chilly. When it is cold outside, people tend to stay inside. With so many people gathered closely together indoors, germs are spread more easily. Germs are spread from person to person, regardless of how cold or warm their bodies are. What is the best summary for the passage?

Diabetes: There are two types of diabetes: Type 1 and Type 2. Both types of diabetes can cause a variety of serious health risks if left untreated. Some of these health problems include kidney disease, blindness, heart disease, and strokes. About 5-10% of people with diabetes have Type 1 diabetes. Type 1 diabetes most commonly develops in young people. In Type 1 diabetes, the immune system destroys the cells in the pancreas that secrete insulin. Without insulin, the body’s cells cannot absorb glucose, and thus cannot produce energy. Symptoms appear after about 90% of the cells have been destroyed. Although most cases of Type 1 diabetes are genetic, some have arisen in people who have had viral infections of the pancreas. Most people who have diabetes (90-95%) have type 2 diabetes, which most commonly develops in people over age 40. Type 2 diabetes results from the inability of tissues to respond to insulin—a condition called insulin resistance. As Type 2 diabetes progresses, the pancreas produces less and less insulin, resulting in a condition called insulin deficiency. There is no cure for either Type 1 or Type 2 diabetes. However, there are ways to manage both types. For Type 1 diabetes, treatment requires receiving regular insulin injections. Type 2 diabetes can also be treated with insulin injections, but can be also be managed with lifestyle changes, such as weight loss, exercise, and reducing intake of carbohydrates. What is the author’s purpose in writing the passage?

Concussions: Concussions are brain injuries that occur when a person receives a blow to the head, face, or neck. Although most people who suffer a concussion experience initial bouts of dizziness, nausea, and drowsiness, these symptoms often disappear after a few days. The long-term effects of concussions, however, are less understood and far more severe. Recent studies suggest that people who suffer multiple concussions are at significant risk for developing chronic traumatic encephalopathy (CTE), a degenerative brain disorder that causes a variety of dangerous mental and emotional problems to arise weeks, months, or even years after the initial injury. These psychological problems can include depression, anxiety, memory loss, inability to concentrate, and aggression. In extreme cases, people suffering from CTE have even committed suicide or homicide. The majority of people who develop these issues are athletes who participate in popular high-impact sports, especially football. Improvements in diagnostic technology have provided substantial evidence to link severe—and often fatal—psychological disorders to the head injuries players receive while on the field. Recent autopsies performed on the brains of football players who have committed suicide have shown advanced cases of CTE in every single victim. In response to the growing understanding of this danger, the National Football League (NFL) has revised its safety regulations. There is hope that these new regulations, coupled with advances in helmet design, will reduce the number of concussions player endure, and thus curb the number of CTE cases. Efforts by the NFL and other professional sports leagues are certainly laudable. However, new regulations at the professional level cannot protect amateur players, especially young people. Fatal cases of CTE have been reported in victims as young as 21. With appropriate equipment and form, tackling need not be dangerous. Proper tackling form—using the arms and shoulders to aim for a player’s midsection rather than leading with the top of the head—should be taught at an early age. Youth, high school, and college leagues should also adopt safety rules even more stringent than the NFL’s. Question: According to the text, what can be inferred in a case involving an athlete with chronic traumatic encephalopathy (CTE)?

GMOs: GMOs, or genetically modified organisms, are organisms whose genes have been altered in laboratories. Scientists modify the genetic codes of plants or animals by inserting copies of desirable genes into the organism’s DNA. While modifying organisms in a laboratory is a relatively new scientific development, people have been experimenting with genetics on plants and animals for centuries. For example, cattle ranchers have selectively bred their animals to produce cows that give more milk. Although some people fear the “Frankenstein” nature of GMOs, there is no scientific evidence to suggest that GMO-based foods are harmful for human consumption. In fact, there are several reasons to believe that GMOs are actually quite beneficial. Through genetic modification, scientists can breed species of plants or animals that yield hardier, more abundant, or even more nutritious food. Geneticists have been able to produce rice plants that can survive droughts and wheat plants that are naturally pest-resistant. Some genetically modified foods have been engineered to have higher levels of specific nutrients, such as protein or calcium. Proponents of GMOs argue that these kinds of advances might one day help to end world hunger. Furthermore, genetically modified crops and animals can be bred to require fewer natural resources and produce less waste. This means that GMOs might also be better for the environment. Question: What is the best summary of this passage?

Understanding Rare Diseases: Although rare diseases are prevalent throughout the global community, they are not given enough attention by the healthcare community. Currently, there are approximately seven thousand rare diseases affecting people all over the world, and they affect nearly thirty million Americans alone. Depending on where someone lives, the definition of a rare disease changes drastically. In the United States, for example, a disease is considered rare if it affects fewer than 200,000 people. In the European Union, however, a disease is only defined as rare if it affects fewer than one in two thousand people. The differences in the mere definition of what a rare disease is can lead to difficulties in diagnoses. Diagnosing a rare disease with certainty can be problematic due to the scarcity of information available as well as a lack of consensus within the healthcare community. Rather than dismissing a patient’s concerns because of a lack of evidence, primary care physicians should be a source of support and help alleviate their patients’ worries over healthcare issues the best they can. It is imperative that general practitioners are well-versed in the area of rare diseases so that they can help affected patients find answers and support. Which supporting detail is an example of opinion, rather than fact?

GMOs: GMOs, or genetically modified organisms, are organisms whose genes have been altered in laboratories. Scientists modify the genetic codes of plants or animals by inserting copies of desirable genes into the organism’s DNA. While modifying organisms in a laboratory is a relatively new scientific development, people have been experimenting with genetics on plants and animals for centuries. For example, cattle ranchers have selectively bred their animals to produce cows that give more milk. Although some people fear the “Frankenstein” nature of GMOs, there is no scientific evidence to suggest that GMO-based foods are harmful for human consumption. In fact, there are several reasons to believe that GMOs are actually quite beneficial. Through genetic modification, scientists can breed species of plants or animals that yield hardier, more abundant, or even more nutritious food. Geneticists have been able to produce rice plants that can survive droughts and wheat plants that are naturally pest-resistant. Some genetically modified foods have been engineered to have higher levels of specific nutrients, such as protein or calcium. Proponents of GMOs argue that these kinds of advances might one day help to end world hunger. Furthermore, genetically modified crops and animals can be bred to require fewer natural resources and produce less waste. This means that GMOs might also be better for the environment. Question: What does the word proponents in the last paragraph mean?

Understanding Rare Diseases: Although rare diseases are prevalent throughout the global community, they are not given enough attention by the healthcare community. Currently, there are approximately seven thousand rare diseases affecting people all over the world, and they affect nearly thirty million Americans alone. Depending on where someone lives, the definition of a rare disease changes drastically. In the United States, for example, a disease is considered rare if it affects fewer than 200,000 people. In the European Union, however, a disease is only defined as rare if it affects fewer than one in two thousand people. The differences in the mere definition of what a rare disease is can lead to difficulties in diagnoses. Diagnosing a rare disease with certainty can be problematic due to the scarcity of information available as well as a lack of consensus within the healthcare community. Rather than dismissing a patient’s concerns because of a lack of evidence, primary care physicians should be a source of support and help alleviate their patients’ worries over healthcare issues the best they can. It is imperative that general practitioners are well-versed in the area of rare diseases so that they can help affected patients find answers and support. Which of the following ideas can be inferred from the passage?

Fibromyalgia: Fibromyalgia is a chronic condition that affects an estimated 3-6% of the world’s population. The disorder is characterized by both physiological and psychological symptoms, including nerve pain, fatigue, sleep and mood disturbances, headaches, bowel problems, and incontinence. The exact cause of fibromyalgia is unknown. For some people, fibromyalgia symptoms begin after some sort of physical or psychological stress. However, for others, the onset of symptoms is gradual. Research has shown that genetics may play a part, but there is also evidence that environmental factors can contribute. The wide variety of symptoms made it difficult to diagnose and treat for many years, though recent research has made some promising advances. Although a cure for fibromyalgia has not yet been developed, research has shown that some of the symptoms can be treated with pharmaceuticals, such as tricyclics or gabapentinoids, or non-pharmacological methods, such as meditation, mindfulness, and cognitive behavior therapy. The most successful pharmacological treatment for fibromyalgia has been tricyclic antidepressants, such as amitriptyline and nortriptyline. These drugs increase the levels of the neurotransmitters serotonin and norepinephrine, which are often found at decreased levels in the brains of people who suffer from chronic pain. By boosting endorphins and relaxing muscles, tricyclics can ease some of the musculoskeletal pain felt by people with fibromyalgia. Question: Which of the following is NOT true according to the passage?

Parkinson’s disease causes muscle rigidity, tremors, dementia, and confusion. Evidence from Johns Hopkins Medicine strengthens the theory that a compound in fruit might prevent and reverse Parkinson’s-related brain damage. Farnesol naturally occurs in herbs and in fruits, including berries. The compound is commonly used in flavoring and perfume production. Mouse studies show promising results in fighting the loss of neurons that produce dopamine. PARIS is a major protein in Parkinson’s disease progression, compromising movement and cognition. Farnesol blocks PARIS, which may be a key in developing new Parkinson’s interventions. In lab experiments, mice that ate farnesol-supplemented diets performed 100% better on a strength and coordination test for Parkinson’s. They also had twice as many healthy dopamine neurons. What is the best summary of the passage?

Mercury in Fish: Mercury is a highly toxic metal found in neon signs, fluorescent lights, older thermometers, and certain kinds of telescopes. It can also be found in something that many people eat on a regular basis: fish. The mercury we might find in a can of tuna is most likely an indirect result of the coal industry. Mercury, which is naturally found in coal, is released into the air when coal is burned. It finds its way into waterways via mercury-laced rain. Mercury accumulates in certain kinds of fish through a process called biomagnification. Biomagnification occurs when a substance enters the food chain in small amounts at the very bottom and then increases in concentration in animals higher up on the food chain. Once a fish eats another creature containing mercury, the mercury does not leave that fish’s body, but instead is stored in fat. Therefore, the mercury continually accumulates as more mercury-contaminated fish are eaten. Despite the toxicity of mercury and the widespread nature of fish contamination, there is no need for the public to be overly apprehensive. Many popular fish, such as salmon, catfish, or tilapia, are generally safe to eat. Other fish, especially tuna and grouper, should only be eaten in moderation. Young children and pregnant women should be especially cautious about how many servings of mercury-contaminated fish they have per week. It is recommended that people in these groups not eat more than 2 servings of mercury-contaminated fish per week. Fish with the highest levels of mercury include shark, swordfish, and king mackerel. All people should avoid eating large amounts of these kinds of fish, and no one should eat these fish more frequently than once a month. Question: Which detail is included regarding safety when eating fish?

GMOs: GMOs, or genetically modified organisms, are organisms whose genes have been altered in laboratories. Scientists modify the genetic codes of plants or animals by inserting copies of desirable genes into the organism’s DNA. While modifying organisms in a laboratory is a relatively new scientific development, people have been experimenting with genetics on plants and animals for centuries. For example, cattle ranchers have selectively bred their animals to produce cows that give more milk. Although some people fear the “Frankenstein” nature of GMOs, there is no scientific evidence to suggest that GMO-based foods are harmful for human consumption. In fact, there are several reasons to believe that GMOs actually quite beneficial. Through genetic modification, scientists can breed species of plants or animals that yield hardier, more abundant, or even more nutritious food. Geneticists have been able to produce rice plants that can survive droughts and wheat plants that are naturally pest-resistant. Some genetically modified foods have been engineered to have higher levels of specific nutrients, such as protein or calcium. Proponents of GMOs argue that these kinds of advances might one day help to end world hunger. Furthermore, genetically modified crops and animals can be bred to require fewer natural resources and produce less waste. This means that GMOs might also be better for the environment. Question: Which of the following is true according to information found in the passage?

Diabetes: There are two types of diabetes: Type 1 and Type 2. Both types of diabetes can cause a variety of serious health risks if left untreated. Some of these health problems include kidney disease, blindness, heart disease, and strokes. About 5-10% of people with diabetes have Type 1 diabetes. Type 1 diabetes most commonly develops in young people. In Type 1 diabetes, the immune system destroys the cells in the pancreas that secrete insulin. Without insulin, the body’s cells cannot absorb glucose, and thus cannot produce energy. Symptoms appear after about 90% of the cells have been destroyed. Although most cases of Type 1 diabetes are genetic, some have arisen in people who have had viral infections of the pancreas. Most people who have diabetes (90-95%) have type 2 diabetes, which most commonly develops in people over age 40. Type 2 diabetes results from the inability of tissues to respond to insulin—a condition called insulin resistance. As Type 2 diabetes progresses, the pancreas produces less and less insulin, resulting in a condition called insulin deficiency. There is no cure for either Type 1 or Type 2 diabetes. However, there are ways to manage both types. For Type 1 diabetes, treatment requires receiving regular insulin injections. Type 2 diabetes can also be treated with insulin injections, but can be also be managed with lifestyle changes, such as weight loss, exercise, and reducing intake of carbohydrates. Which detail provides scientific reasoning to support the idea that “diabetes can cause a variety of health risks if left untreated”?

Fibromyalgia: Fibromyalgia is a chronic condition that affects an estimated 3-6% of the world’s population. The disorder is characterized by both physiological and psychological symptoms, including nerve pain, fatigue, sleep and mood disturbances, headaches, bowel problems, and incontinence. The exact cause of fibromyalgia is unknown. For some people, fibromyalgia symptoms begin after some sort of physical or psychological stress. However, for others, the onset of symptoms is gradual. Research has shown that genetics may play a part, but there is also evidence that environmental factors can contribute. The wide variety of symptoms made it difficult to diagnose and treat for many years, though recent research has made some promising advances. Although a cure for fibromyalgia has not yet been developed, research has shown that some of the symptoms can be treated with pharmaceuticals, such as tricyclics or gabapentinoids, or non-pharmacological methods, such as meditation, mindfulness, and cognitive behavior therapy. The most successful pharmacological treatment for fibromyalgia has been tricyclic antidepressants, such as amitriptyline and nortriptyline. These drugs increase the levels of the neurotransmitters serotonin and norepinephrine, which are often found at decreased levels in the brains of people who suffer from chronic pain. By boosting endorphins and relaxing muscles, tricyclics can ease some of the musculoskeletal pain felt by people with fibromyalgia. Question: What is the best summary of the passage?

Does Low Body Temperature Cause Illness?: As children, we are often told to dress warmly in the winter so we do not get sick. This is a common piece of advice, but is there any truth behind it? In fact, there is no scientific evidence to suggest that being cold can get you sick. Most illnesses are caused by viruses and bacteria. Illnesses like strep throat, influenza, and the common cold are only spread through contact with other infected people. How cold you are when you come into contact with the virus or bacteria has nothing to do with whether or not you will get sick. The effect of body temperature on contracting illness was tested on human beings in the 1950s. Researchers divided volunteers into two groups: half of them were kept in a warm room and the other half were kept in a cold room. Both groups were then exposed to rhinovirus–the virus responsible for the common cold. The researchers discovered that members of both groups developed colds at the same rate. Since that first experiment, there have been similar experiments performed with a variety of different illnesses. All have yielded the same result: being cold does not make a person more likely to get sick. Of course, it does seem that people do get sick more often when the weather is cold. However, this is because there is some evidence that people do get sick more often in cold weather, but it has nothing to do with forgetting to bundle up when it is chilly. When it is cold outside, people tend to stay inside. With so many people gathered closely together indoors, germs are spread more easily. Germs are spread from person to person, regardless of how cold or warm their bodies are. Which word would best replace ‘yielded’ in paragraph 2?

A True Renaissance Man: Have you ever heard the term, “Renaissance Man”? This phrase developed in Italy during the Renaissance period (from the 14th century to the 17th century) and was used to describe a person who embraced a great deal of knowledge across a variety of disciplines. Galileo Galilei, the Italian astronomer, physicist, and engineer is perhaps the best example of a true Renaissance Man. Not only did he study a wide range of academic subjects, ranging from mathematics to linguistics, but he was also courageous enough to challenge scientific theories that existed at the time. Galileo’s most famous discovery debunked the most widely-held belief during that period: that the Earth was located in the center of the universe. His scientific findings and ideas showing that the Sun was actually the center of the universe ultimately caused him to become the target of the Inquisition, an official religious investigation against ideas that contradicted the Catholic church. After being charged with heresy, most of Galileo’s writings were banned and he spent the remainder of his life in prison. Despite this unjust and harsh treatment, he is now celebrated as one of the greatest minds of all time, as well as the “father” of modern science. Unfortunately, Galileo was not the only scholar to have undergone this punishment for challenging the status quo during that time. Thankfully, justice has finally been served to a great “Renaissance Man”. Based on the passage, what can be inferred regarding the acceptance of ideas that challenged existing principles during the time of Galileo?

A True Renaissance Man: Have you ever heard the term, “Renaissance Man”? This phrase developed in Italy during the Renaissance period (from the 14th century to the 17th century) and was used to describe a person who embraced a great deal of knowledge across a variety of disciplines. Galileo Galilei, the Italian astronomer, physicist, and engineer is perhaps the best example of a true Renaissance Man. Not only did he study a wide range of academic subjects, ranging from mathematics to linguistics, but he was also courageous enough to challenge scientific theories that existed at the time. Galileo’s most famous discovery debunked the most widely-held belief during that period: that the Earth was located in the center of the universe. His scientific findings and ideas showing that the Sun was actually the center of the universe ultimately caused him to become the target of the Inquisition, an official religious investigation against ideas that contradicted the Catholic church. After being charged with heresy, most of Galileo’s writings were banned and he spent the remainder of his life in prison. Despite this unjust and harsh treatment, he is now celebrated as one of the greatest minds of all time, as well as the “father” of modern science. Unfortunately, Galileo was not the only scholar to have undergone this punishment for challenging the status quo during that time. Thankfully, justice has finally been served to a great “Renaissance Man”. What is the author’s purpose for writing this paragraph?

A True Renaissance Man: Have you ever heard the term, “Renaissance Man”? This phrase developed in Italy during the Renaissance period (from the 14th century to the 17th century) and was used to describe a person who embraced a great deal of knowledge across a variety of disciplines. Galileo Galilei, the Italian astronomer, physicist, and engineer is perhaps the best example of a true Renaissance Man. Not only did he study a wide range of academic subjects, ranging from mathematics to linguistics, but he was also courageous enough to challenge scientific theories that existed at the time. Galileo’s most famous discovery debunked the most widely-held belief during that period: that the Earth was located in the center of the universe. His scientific findings and ideas showing that the Sun was actually the center of the universe ultimately caused him to become the target of the Inquisition, an official religious investigation against ideas that contradicted the Catholic church. After being charged with heresy, most of Galileo’s writings were banned and he spent the remainder of his life in prison. Despite this unjust and harsh treatment, he is now celebrated as one of the greatest minds of all time, as well as the “father” of modern science. Unfortunately, Galileo was not the only scholar to have undergone this punishment for challenging the status quo during that time. Thankfully, justice has finally been served to a great “Renaissance Man”. Which of the following statements would the author most likely agree with?