AMT MLS Domain 4: Coagulation and Hemostasis Welcome to your AMT MLS Domain 4: Coagulation and Hemostasis 1. AMT MLS: Coagulation and Hemostasis What is the role of thrombomodulin in the coagulation cascade? It activates protein C. It converts fibrinogen to fibrin. It catalyzes the conversion of prothrombin to thrombin. It serves as a cofactor for factor VIII. None 2. AMT MLS: Coagulation and Hemostasis Which of the following laboratory findings is most consistent with Disseminated Intravascular Coagulation 'DIC'? Prolonged PT, normal aPTT, decreased fibrinogen, and normal D-dimer Prolonged PT, prolonged aPTT, decreased fibrinogen, and increased D-dimer Normal PT, normal aPTT, increased fibrinogen, and normal D-dimer Prolonged PT, normal aPTT, increased fibrinogen, and decreased D-dimer None 3. AMT MLS: Coagulation and Hemostasis What is the primary function of von Willebrand factor (vWF) in hemostasis? It catalyzes the conversion of fibrinogen to fibrin. It mediates platelet adhesion to the subendothelial matrix. It serves as a cofactor for the activation of factor X. It accelerates the degradation of factor VIII. None 4. AMT MLS: Coagulation and Hemostasis In the context of coagulation, what is the primary role of tissue factor? It activates factor VII. It converts prothrombin to thrombin. It is a cofactor for factor XIII. It inhibits protein C activation. None 5. AMT MLS: Coagulation and Hemostasis Which test is primarily used to assess the intrinsic pathway of the coagulation system? Prothrombin Time (PT) Activated Partial Thromboplastin Time (aPTT) Thrombin Time (TT) Platelet Function Analysis (PFA) None 6. AMT MLS: Coagulation and Hemostasis What is the primary effect of activated protein C in the coagulation process? It converts fibrinogen to fibrin. It promotes platelet aggregation. It inactivates factors Va and VIIIa. It activates factor VII. None 7. AMT MLS: Coagulation and Hemostasis Which factor is involved in stabilizing the fibrin clot? Factor V Factor VII Factor XIII Factor IX None 8. AMT MLS: Coagulation and Hemostasis What is the significance of the D-dimer test in clinical practice? It is used to diagnose hemophilia A. It confirms the presence of an acute thrombotic event. It measures the amount of circulating fibrinogen. It assesses the efficacy of anticoagulant therapy. None 9. AMT MLS: Coagulation and Hemostasis What role does factor XII play in coagulation? Initiates the extrinsic pathway. Acts as a cofactor for factor VII activation. Initiates the intrinsic pathway. Converts prothrombin to thrombin. None 10. AMT MLS: Coagulation and Hemostasis Which coagulation factor deficiency is associated with hemophilia B? Factor VIII Factor IX Factor X Factor XI None 1 out of 10 Time is Up! Time's up
