AMT MLS Domain 3: Hematology Welcome to your AMT MLS Domain 3: Hematology 1. AMT MLS: Hematology When evaluating a peripheral blood smear, the presence of which of the following cells is indicative of a severe allergic reaction or parasitic infection? Neutrophils Eosinophils Basophils Monocytes None 2. AMT MLS: Hematology Which of the following genetic mutations is most commonly associated with Chronic Myelogenous Leukemia (CML)? JAK2 V617F mutation BCR-ABL fusion gene FLT3-ITD mutation PML-RARA fusion gene None 3. AMT MLS: Hematology In the context of hemostasis, which pathway is primarily assessed by the Prothrombin Time (PT) test? Intrinsic pathway Extrinsic pathway Common pathway Fibrinolytic pathway None 4. AMT MLS: Hematology Howell-Jolly bodies are seen in patients with: Hemolytic anemia Sickle cell anemia Iron deficiency anemia Megaloblastic anemia None 5. AMT MLS: Hematology The presence of Heinz bodies is indicative of which of the following conditions? G6PD deficiency Hemophilia A Vitamin B12 deficiency Acute lymphoblastic leukemia None 6. AMT MLS: Hematology What is the primary function of von Willebrand factor in hemostasis? Catalyzes the conversion of fibrinogen to fibrin Acts as a carrier for factor VIII Promotes platelet adhesion to the subendothelium Activates the intrinsic pathway None 7. AMT MLS: Hematology The Philadelphia chromosome is a result of which chromosomal translocation? t(9;22)(q34;q11) t(15;17)(q22;q12) t(8;21)(q22;q22) t(14;18)(q32;q21) None 8. AMT MLS: Hematology Reed-Sternberg cells are characteristic of which type of lymphoma? Hodgkin's lymphoma Non-Hodgkin's lymphoma Burkitt's lymphoma Mantle cell lymphoma None 9. AMT MLS: Hematology The coagulation factor deficiency in Hemophilia A affects which pathway? Intrinsic pathway Extrinsic pathway Common pathway Fibrinolytic pathway None 10. AMT MLS: Hematology Which of the following is a major criterion for the diagnosis of polycythemia vera? Elevated white blood cell count Low erythropoietin level Elevated red blood cell mass Elevated platelet count None 11. AMT MLS: Hematology In a patient with suspected disseminated intravascular coagulation 'DIC', which laboratory finding is typically observed? Increased fibrinogen level Decreased D-dimer Prolonged PT and aPTT Increased platelet count None 12. AMT MLS: Hematology Which of the following is characteristic of a leukemoid reaction? Decreased leukocyte alkaline phosphatase (LAP) score Presence of the Philadelphia chromosome Elevated white blood cell count Low neutrophil count None 13. AMT MLS: Hematology The M:E ratio in bone marrow refers to the ratio of: Myeloblasts to erythroblasts Megakaryocytes to erythrocytes Myeloid cells to erythroid cells Monocytes to eosinophils None 14. AMT MLS: Hematology In which condition is the presence of schistocytes typically observed on a peripheral blood smear? Hemolytic uremic syndrome Chronic lymphocytic leukemia Iron deficiency anemia Thalassemia None 15. AMT MLS: Hematology Target cells are commonly seen in which of the following conditions? Acute myeloid leukemia Thalassemia Polycythemia vera Vitamin B12 deficiency None 1 out of 15 Time is Up! Time's up
